Naltrexone in Primary Hyperphagic Obesity Wity Hypochondriacal Disorder - a Clinical Study
نویسندگان
چکیده
Six well investigated patients of primary hyperphagic obesity with hypochondrical disorder were sequentially treated with psychoeducational methods alone and psychoeducational methods with naltrexone hydrochloride 50 mg daily orally for six weeks each. RMANOVA revealed no statically significant (p>0.05) decrease in body mass index suggesting that psychoeducational methods with naltrexone were as ineffective in reducing obesity as psychoeducational methods alone. The limitations of the study and implications for future research are discussed.
منابع مشابه
Comparative Study on the Effect of Risperidone and its Combination with Naltrexone in Pediatric Patients with Autistic Spectrum Disorders: A Clinical Trial Study
Background Autistic spectrum disorder (ASD) refers to a syndrome associated with persistent impairments in communication skills, social interactions, and so forth. Given the approval of risperidone and naltrexone by U.S. Food and Drug Administration (FDA) for ASD cases and extant controversy concerning their pertained side effects, this double-blind, placebo-controlled, crossover clinical trial...
متن کاملAssessment of hyperphagia in Prader-Willi syndrome.
OBJECTIVE Prader-Willi syndrome (PWS), the leading known genetic cause of obesity, is characterized by intellectual disabilities, maladaptive and compulsive behaviors, and hyperphagia. Although complications of obesity resulting from hyperphagia are the leading cause of death in PWS, quantifying this drive for food has long been an unmet research need. This study provides factor-analytic and wi...
متن کاملNaltrexone/Bupropion
In March 2010, Orexigen(R) Therapeutics submitted a new drug application (NDA) for approval of naltrexone sustained release (SR)/bupropion SR (Contrave(R)) for the treatment of obesity in the US. The tablet contains naltrexone SR 32 mg and bupropion SR 360 mg. The drug has been tested in four randomized, double-blind, placebo-controlled, phase III trials and the co-primary endpoints were met in...
متن کاملافکار خود بیمار پندارانه در افراد مبتلا به اختلالات اضطرابی و افسردگی ماژور
Abstract Backgrounds & Aims: The purpose of this study was to comparison degree of hypochondriacal thought in patients with anxiety disorders and depression. Materials & Methods : In this study, 156 patients with anxiety disorders and depression were selected by convenience sampling method. Illness attitude scales (IAS) was administrated to them. Data analysis was done using covariance and ...
متن کاملThe Study of the Demographic and Clinical and Laboratory Findings in Naltrexone Poisoning Patients Admitted to Razi Hospital, Rasht, During 2007-08
Background:Naltrexone is a competitive opioid receptor antagonist blocking the euphoric effects of exogenous opioids. When used concomitantly with opioids, naltrexone causes severe withdrawal symptoms.The main aim of the study is to determine the symptomatology and outcome of patients who consumed naltrexone in conjunction with an opioid substance. Methods:This cross-sectional study was perf...
متن کامل